eCFR Reference Browser

---

title: "21 CFR §189.280"

source: "https://www.ecfr.gov/current/title-21/section-189.280"

title_number: "21"

volume_number: "3"

chapter_number: "Unknown"

subchapter_code: "B"

subchapter_subject: "FOOD FOR HUMAN CONSUMPTION (CONTINUED)"

part_code: "189"

part_subject: "SUBSTANCES PROHIBITED FROM USE IN HUMAN FOOD"

subpart_code: "D"

subpart_subject: "Substances Prohibited From Indirect Addition to Human Food Through Food-Contact Surfaces"

section_number: "189.280"

section_subject: "4,4′-Methylenebis (2-chloroanaline)."

cfr_reference: "21 CFR 189.280"

title_name: "Title 21"

title_subject: "Food and Drugs"

parts_covered: "Parts 170 to 199"

revised_date: "Revised as of April 1, 2019"

publication_date: "As of April 1, 2019"

contains_description: "Containing a codification of documents of general applicability and future effect"

publication_info: "Published by the Office of the Federal Register National Archives and Records Administration as a Special Edition of the Federal Register"

---

(a)4,4′-Methylenebis (2-chloroanaline) has the molecular formula, C13H12Cl2N2. It is a synthetic chemical not found in natural products and has been used as a polyurethane curing agent and as a component of food packaging adhesives and polyurethane resins.

(b)Food containing any added or detectable level of this substance is deemed to be adulterated in violation of the act based upon an order published in the Federal Register of December 2, 1969 (34 FR 19073).

§189.280 - 4,4′-Methylenebis (2-chloro­analine).

§189.280 - 4,4′-Methylenebis (2-chloroanaline).